Low weight. Weight less than 3rd percentile. Hearing defect. Hunched back. Round back. Decreased body height. Small stature. Do you have more information about symptoms of this disease? We want to hear from you. Do you have updated information on this disease? Find a Specialist Find a Specialist. Healthcare Resources To find a medical professional who specializes in genetics, you can ask your doctor for a referral or you can search for one yourself.
You can also learn more about genetic consultations from MedlinePlus Genetics. Learn More Learn More. In-Depth Information The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health.
Visit the website to explore the biology of this condition. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. Orphanet is a European reference portal for information on rare diseases and orphan drugs.
Access to this database is free of charge. PubMed is a searchable database of medical literature and lists journal articles that discuss Ramon Syndrome. Click on the link to view a sample search on this topic. Have a question? Share this content:. Close Copy Link. You May Be Interested In. How to Find a Disease Specialist. Tips for the Undiagnosed. Support for Patients and Families.
Tips for Finding Financial Aid. Help with Travel Costs. How to Get Involved in Research. Medical and Science Glossaries. Caring for Your Patient with a Rare Disease. FindZebra Diagnosis Assist Tool. Finding Funding Opportunities. Teaching Resources. The pain was accompanied by tearing of the left eye and left copious nasal discharge.
She had on examination sensitivity to tactile stimuli which produced severe paroxysmal pain in the second division territory repetitively when triggered from a left nasolabial fold trigger point. There was no response to phenytoin mgs. The patient refused further medical and surgical treatment. Case D. A year-old woman who was seen regarding pain in the right upper lateral lip around the corner of the mouth which she had had for about a year.
The pain consisted of many lancinating jabs triggered by brushing the teeth and washing the face and eating, and radiated to the right eye. It was totally relieved by carbamazepine in a dose of mgs. Six months later she began to have pain in the left upper lip radiating to the left eye of a similar nature, again responding to carbamazepine which she had stopped taking.
Ten months following the initial visit she began to have steady severe pain in the right second division territory, encompassing the entire area of V This was aggravated by talking and eating but was not shock-like.
It was steady and tended to last all day. She declined any medical treatment for that at that time. Twelve months later she developed a clear resurgence of left second division tic douloureux which occurred in the malar region just below the eye. It was triggered by brushing the teeth, eating and washing her face and responded to carbamazepine mgs. Two years after the initial visit, she developed left facial pain in the second division territory, located in the upper gums, radiating to the left eye and temple.
It was a severe steady pain which lasted steadily and severely for one hour and occurred about twice a day, frequently wakening her from her sleep over a two-week period. During this severe burning steady pain, she noticed that her left eye became red and teared copiously, and the left nostril became obstructed. No triggered lancinating pain was present. She claimed no effect from carbamazepine mgs. The pain became much worse after stopping the carbamazepine, and a tic-like component to the pain emerged with triggered lancinating jabs in the cheek on the left.
Reinstitution of carbamazepine t. The pain became controlled with that for one month. She was not happy with taking medication, so she elected to have a posterior fossa exploration. This revealed that a loop of the superior cerebellar artery was found pushing up against the trigeminal root on its superior medial aspect. A sponge was placed between the kinking of the artery and the nerve root and the patient has had complete relief of pain at three months follow-up.
Case E. A year-old man with a two-year history of severe right-sided headaches occurring once to twice a day lasting one to two hours each. They were steady, severe and often occurred at night. They were located over and behind the right eye and radiated to the right ear. They were accompanied by injection of the sclera, copious tearing of the right eye and right-sided nasal congestion. Cold air on the face, washing the face or tactile stimulus on the skin just below the right eye triggered lancinating pain above, behind, below and lateral to the right eye.
It was possible to repetitively trigger lancinating pain by tactile stimulation of a trigger point just below the right eye. The patients consisted of 6 females and 7 males with one patient's sex not noted in the case report. Their median age was 44 years range Four patients Cases 1, 4, A, D were examples of an initial presentation of tic douloureux with the later occurrence of cluster headache.
One case began as cluster and later developed tic douloureux Case 5. Eight cases Case 2, 6, 7, 8, 9, B, C, E had combined features of the two disorders, either with the same attack of pain or at separate times. In one case the temporal features could not be determined. The territory of the second division of the trigeminal nerve V 2 was most commonly affected with both the cluster and tic components of the pain. Carbamazepine is capable of relieving both components of the pain Cases 4 and B, the latter case for only two months.
It controlled the tic component in three, when the tic occurred alone Case A or when mixed in with cluster episodes Cases 7, 8. This drug was tried and failed in three Cases C, D, E. Baclofen alone gave almost complete relief in one cluster-tic for two months Case B who had surgery because he didn't like taking pills. Baclofen plus carbamazepine controlled Case D cluster-tic for one month but she elected surgery because of antipathy to pills.
It is not possible to draw conclusions from the variety of other drugs indicated in Table 1. Twelve operations were performed in eight patients. Trigeminal rhizotomy relieved the tic component to the pain in all four instances Cases 1, 4, 5, 6 , relieving the cluster in the only two cases 1, 6 in which it cluster occurred.
Oral Surg. ORPHA: ;. Ramon et al. NOTE: OMIM is intended for use primarily by physicians and other professionals concerned with genetic disorders, by genetics researchers, and by advanced students in science and medicine. While the OMIM database is open to the public, users seeking information about a personal medical or genetic condition are urged to consult with a qualified physician for diagnosis and for answers to personal questions.
Printed: Jan. To ensure long-term funding for the OMIM project, we have diversified our revenue stream. We are determined to keep this website freely accessible. Unfortunately, it is not free to produce. Expert curators review the literature and organize it to facilitate your work.
Please join your colleagues by making a donation now and again in the future. Donations are an important component of our efforts to ensure long-term funding to provide you the information that you need at your fingertips. Toggle navigation. A bonus to all MIMmatch users is the option to sign up for updates on new gene-phenotype relationships.
Clinical Trials.
0コメント